On-going Extramural Research Projects

Project Code	Principal Investigator (PI), Co-PI, if any	Funding Agency	Title of the Project	Objectives	Amount Received (INR (in Lacs.))
GP-252	Dr. U. C. Banerjee	-	-	-	419.82
GP-398	Dr. M. E. Sobhia	DST	The challenges of new drug discovery for oral anti diabetic drugs: Molecular dynamics simulations, pharmacophore modeling and molecular design of PTP1B allosteric inhibitors.	Details	25.00
GP-399	Dr. M. E. Sobhia	CSIR	Studies on PTPIB allosteric inhibitors: In silico design, biological applications and protein crystallization.	Details	14.82
GP-400	Dr. Arvind K Bansal	DST	Development and evaluation of Nanocrystalline Solid Dispersion of a poorly water soluble drug.	Details	17.00
GP-401	Dr. J. K. Laha	SERB	Development of metal - catalyzed domino synthesis of azafluorenes and its applications in the synthesis of compounds potential as aromatase inhibitors, natural product, and in the discovery of new amine protecting group.	Details	46.50
GP-404	Dr. A. H. Pande	DST	Generation and characterization of improved variant(s) of SsoPox enzyme as organophoaphate - degrading agent.	Details	25.00
GP-405	Dr. Sankar K. Guchhait	CSIR	Natural product inspired novel heterocyclic antitubulin anticancer agents: Design, synthesis and bio - evaluation studies.	Details	10.50
GP-406	Dr. Arvind K Bansal Dr. A.T. Sangamwar (Co-PI)	DBT	Nanocrystalline solid dispersion of polyphenols (curcumin and hesperetin) with enhanced oral bioavailability for cancer treatment.	Details	11.88
GP-407	Dr. Ipsita Roy	SERB	Exploring the role of aging on chaperone - mediated protein folding in a yeast model of Huntington's disease.	Details	26.25
GP-408	Dr. P. V. Bharatam	DST	Multiscale modelling of pharmaceutically relevant drug dendrimer nano scale complexes.	Details	40.00
GP-409	Dr. Inder Pal Singh	DIHAR-DRDO	Biologically active secondary metabolites from Codonopsis clematidea of trans Himalayas.	Details	6.50
GP-410	Dr. Ipsita Roy	DBT	Regulated expression of RNA aptamers for inhibition of protein aggregation.	Details	36.98
GP-411	Dr. Inder Pal Singh, Sanjai Saxena (Thapar University, Patiala) Dr. Manmohan Chhibber (Co-PI)	DBT	Isolation and characterization of xanthine oxidase inhibitors from endophytic fungi for treatment of hyperurecemia and gout.	Details	13.70
GP-412	Dr. Dipika Bansal Dr. Prabha Garg (Co-PI)	ICMR	Comparative efficacy, safety and Generalized cost-effectiveness of commonly used medications in Chronic Low Back Pain: A Bayesian multiple treatment comparison analysis.	Details	4.21
GP-413	Dr. K B Tikoo	SERB	Elucidation of role of DNA methylation in emergence of insulin resistance.	Details	23.95
GP-414	Dr. G. B. Jena	DST	Influence of Nrf2-ARE signaling pathways on the genetic and epigenetic modifications in the germ cells of diabetic rat: Role of zinc and selenium.	Details	10.53
GP-415	Dr. Arvind K Bansal	BIRAC	Enhancement of oral bioavailability of poorly water soluble drugs using NanoCrySP* technology, *A patented nanocrystalline solid dispersion technology platform developed at NIPER, S.A.S. Nagar.	Details	31.10
GP-416	Dr. Sankar K. Guchhait	SERB	Switch in mode of action of Ellipticine with Etoposide-inspired structural modulation: Towards exploration of new molecular motifs as potential anticancer agents.	Details	27.35
GP-417	Dr. A. T. Sangamwar	DBT	Computational and in vitro screening of bioflavonoids for selective P-gp inhibition.	Details	15.40
GP-418	Dr. Chaaya Iyengar	DBT (NWBA)	Mutagenesis of M.tuberculosis Glyceraldehyde-3-phosphate dehydrogenase (M.tb GAPDH) to identify key residues involved in protein multifunctionality.	Details	5.00
GP-419	Dr. Chaaya Iyengar Dr. Ipsita Roy (Co-PI)	DBT	Regulation and Mechanism of M.tb Glyceraldehyde-3-phosphate dehydrogenase in transferrin iron uptake.	Details	24.77
GP-420	Prof. I. P. Singh, Dr. Dharamvir Arya (AIIMS, New Delhi) Dr. Kulbhushan Tikoo, Prof. Arvind Bansal, Dr. Dinesh Kumar (IHBT) (Co-PI) Prof. Kamlesh Bhutani, Prof. Sanjay Jachak, Dr. Mahesh Gupta (IHBT), Dr. G. B. Jena, Dr. Ashok Singh (IHBT), Dr. Ruma Ray (AIIMS), Dr. Tapas Nag (AIIMS), Dr. Jagriti Bhatia (AIIMS)	DBT	Development of herbal formulations from Seabuckthorn.	Details	98.89
GP-421	Dr. Sanyog Jain	DST	Lipid conjugate based & nontech driven approaches for oral /systemic delivery of amphotericin B in efficient management of visceral leishmaniasis & systemic fungal infection.	Details	37.07
GP-422	Dr. Arvind K Bansal	ICMR	Pre-clinical Development of Penicillin Drug Delivery System for Prophylaxis of Rheumatic Heart Disease.	Details	32.24
GP-423	Dr. Chaaya Iyengar	DST	Lactoferrin mediated iron uptake via Mycobacterium tuberculosis Glyceraldehyde-3-phophate dehydrogenase.	Details	7.62
GP-424	Dr. Sanyog Jain	BIRAC SRISTI GYTI	Design and development of novel protein stabilized multiple emulsion with permeation enhancer to improve oral bioavailability of insulin.	Details	3.75
CNF-160	Dr. Sanyog Jain Dr. Rajan Swamy (Post Doc)	SERB	Advanced non viral nano-nucleotherapeutics to enhance gene silencing through localised cytoplasmic delivery.	Details	9.60
CNF-161	Dr. Sanyog Jain Dr. K B Tikoo (Mentor)	SERB	Development of RNA aptamer conjugated nanoparticle-5hmdC and 5fdC targeting cytidine deaminase expressing cancer cells.	Details	18.70
CNF-162	Dr. Saima Malik	SERB	Synthesis of Marine Alkaloid Mansouramycin D and Structure Activity Relationship (SAR) study.	Details	9.60