Generation of benzyl and acyl radicals, radical cations largely using persulfates, especially their reactions in water, mechanistic study to understand their generation, umpolung reactivity of reactive radical intermediates, and their applications to the synthesis of heterocycles and generic active pharmaceutical ingredients (APIs)

Understanding organic chemistry of drug degradations and interactions

New process development for the synthesis of generic drugs and drug intermediates (APIs) utilizing novel catalytic C-H functionalizations, Tandem/Domino/Cascade reactions, or via C-H bond activation

Design and synthesis of biaryl sulfonamides, atropisomerism in biaryl sulfonamdies, preparation of sultams and their ring opening via thermal or photochemical reactions, chemo-enzymatic ring opening of sultams